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Young Women With Multiple Myeloma at Highest Risk for Nausea and Pain From Stem Cell Transplant

Posted on March 18 2010 by Pat Killingsworth | 1,340 views

I did not know that woman are at higher risk for pain and nausea following a SCT.  (Don’t be confused–a SCT and HSCT are the same thing–a stem cell transplant) Here is part of an article I read today on Medscape Medical News today:

March 16, 2010 (Atlanta, Georgia) — Researchers have identified predictors of adverse symptoms in cancer patients undergoing hematopoietic stem cell transplantation (HSCT) and found that being female, having multiple myeloma, and being younger increase the risk for pain and nausea.

Susan Bauer-Wu, PhD, RN, associate professor of nursing at Emory University, in Atlanta, Georgia, presented the research findings here at the 16th International Conference on Cancer Nursing.

The researchers described the symptom experience of 73 HSCT patients over time, measuring 4 time points, from before hospitalization until 45 days after transplant. Of the patients, 52% had lymphoma and 48% had multiple myeloma.

The Symptom Experience Scale was used to measure 3 parameters (frequency, intensity, and distress) of cancer-related physical symptoms, including nausea, sleep disturbance, and pain.

In cancer patients undergoing HSCT, women experienced more pain and nausea than men; multiple myeloma patients experienced more symptoms than patients with lymphoma; and younger patients experienced more pain than older patients.

Read more by going to:  Medscape Today-Women with Multiple Myeloma.
Feel good, keep smiling and hope you gals out there with multiple myeloma don’t need a HSCT anytime soon!  Pat

9 Comments For This Post

  1. feresaknit Says:

    Well that's something to look forward to. At least I know I won't just be beng mard. 😉

  2. Pat Killingsworth Says:

    I'm guessing this comment is from a woman. These results would bum me out, too! Pat

  3. feresaknit Says:

    You guessed right and a young one at that, well certainly by myeloma standards. It's harvest time on Monday and replanting after Easter. I'm going to print your post off and take it with me so I can justify any moaning I do! Paula

  4. Kristine Says:

    how young is young? I'm a 45 year old woman diagnosed 10/08. Have had two SCT. undergoing maintenance treatment. VTD. My biggest complaint through al of this has been pain and fatigue. My oncologist can't explain it. I have been charting the "painful days" but there doesn't seem to be much of a pattern. Well at least nausea hasn't been much of an issue so I will count that as a blessing.

  5. Pat Killingsworth Says:

    Paula-
    I am on the road so couldn't respond right away… So sorry you have to go through all this! I've never heard the term "replanting"… I had my harvest before several of the new stem cell mobilization drugs were developed–also had radiation and Revlimid therapy prior to collection. It went slow–much slower than I would expect yours to go. I'm glad you are taking some time between harvest and transplant. Going right to transplant can be a lot for one's body to endure. Have you ever considered waiting after harvest? Hate to bring it up and play with your head… I'm just saying, waiting can sometimes be an option. Call me: 866-336-1686 anytime if you like. Hey, good luck! I will be thinking about you! Pat

  6. Pat Killingsworth Says:

    Kristine-
    Not that it really changes anything, but this study may at least explain some of your pain. Sometimes it helps to know why–or at least that you aren't alone. How is your maintenance going? And why such a potent post-transplant cocktail? Were you high risk? Or U of Arkansas patient, maybe? Either way, you must be strong and determined. You go girl! Feel better and good luck to you, too- Pat

  7. Kristine Says:

    I am being treated at Huntsman in Utah by Dr. Tricot who came from Arkansas. Just finished eighth month of maintenance treatment. I have four more months if I can stand it. I have been able to manage most of the side effects-managing three teenage boys now that's a different story. Thank goodness I have an amazing husband. I'm taking May off of treatment to prepare for my daughters wedding. I'm sure it will be very tempting to discontinue "the plan." Dr. Tricot is very encouraging and seems to think that we should be able to knock this into a long remission, and as he says in his belgian accent, "a possible cure." I'm doing what I have to and hoping that I can be around to enjoy my family and my life.

  8. feresaknit Says:

    Hi Pat – Thanks for messing with my head! I came within a hair's breadth of ringing you, even looking up what the time difference was! I decided I was going to go ahead and with a bit of a delay go in tomorrow. I have had a gap since the last chemo in November for a completely unsuccessful stem cell production and had Plerixafor in March which gave my little stem cells a suitable kick up the backside. I really appreciate you giving your number even though I didn't use it. Paula

    NB – I have printed your post off to take with me! ;D

  9. Pat and Pattie Killingsworth Says:

    Good luck! And seriously, while you are sitting in the waiting room, give me a call if you like- Pat

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