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Monthly Archives: November 2010

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30 11, 2010

Pfizer To Present Multiple Myeloma Related Phase 1 Results Evaluating PD0332991 At ASH

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While I was researching my pre-ASH article on our Help With Cancer.org site this morning (that is where I post non-myeloma related cancer news from large oncology conferences like ASH and ASCO), I found this interesting tidbit burried deep in one of Pfizer's press releases:A Phase 1 trial evaluating PD 0332991 in combination with bortezomib

29 11, 2010

What Multiple Myleloma Patients Should Look For When Reading Press Releases From The ASH Meetings In Orlando

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It's ASH week!  In four days, hematologists, oncologists, researchers and reporters from all over the world will converge on Orlando, Florida's International Drive to share the latest developments involving blood related disorders at the annual American Society of Hematology meetings.  I will be in Orlando Thursday getting ready for the weekend's meetings as well.The pre-ASH press releases

28 11, 2010

List Of Over 100 Multiple Myeloma Related Clinical Trials

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Trialx.com features a helpful, comprehensive multiple myeloma related guide on Cure Talk.  Here is a link to their site:  List of Multiple Myeloma Clinical Trials and Treatments. Basic, but a helpful resource.  I especially appreciated the section showing which cancer centers featured multiple myeloma related studies:   List of Common Multiple Myeloma Clinical Trial Lead Sponsors

27 11, 2010

Review About Using Anti-Bodies In Multiple Myeloma Therapy

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I have recieved a number of e-mail questions about the potential of using anti-bodies against multiple myeloma.  Here is an article I wrote in June following the large ASCO conference in Chicago which addressed this question:New Research Study Focuses On Antibodies To Stop Multiple MyelomaUpdate on another new anti-myeloma research study, post ASCO:Immunomedics doses first

23 11, 2010

Follow-Up Comments From Institute for Myeloma & Bone Cancer Research Executive Director Geoffrey Gee

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I just received this e-mail in response to Sunday's article, Research Targets Pleiotrophin In Promising Anti-Myeloma Therapy, about how the Institute for Myeloma & Bone Cancer Research was working to develop a cure for multiple myeloma:Pat- Just wanted to throw in my two cents worth. This is how I express our focus: The Cure Myeloma Project

22 11, 2010

Australian Study Links High Levels Of Uric Acid To Stronger, Denser Bones In Men

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Here is another interesting research finding about bone strength/health from Australia's Rheumatology Update:High uric acid promotes bone healthHigher serum uric acid levels inolder men are strongly associatedwith increased bone mineraldensity (BMD) and markers ofcalcium homoeostasis and boneresorption, landmark Australianresearch has shown.A study led by Professor MarkusSeibel at the ANZAC ResearchInstitute in Sydney examined 1,705community-dwelling men

21 11, 2010

Research Targets Pleiotrophin In Promising Anti-Myeloma Therapy

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Haiming Chen, MD., Ph.D and Director of the Institute for Myeloma & Bone Cancer Research Laboratory in Los Angeles, California claims to have found a possible link to a cure for multiple myeloma.  The Intitute's spokesperson, Cheryl Cross, describes the process this way:Dr. Chen's research discovered that myeloma tumors produce a protein, pleiotrophin, that assists

20 11, 2010

Follow-Up To Yesterday’s Announcement About FDA Approval Of Denosumab

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Yesterday morning I wrote an article about how the FDA had approved denosumab (Xgeva) for use in some cancers, but not multiple myeloma.  The Myeloma Beacon also published a story about denosumab later yesterday evening:Xgeva Receives FDA Approval For Bone Disease In Solid Tumors, But Not Multiple MyelomaMyeloma Beacon reporter Julie Shilane was able to interview someone

19 11, 2010

FDA Approves New Cancer Bone Drug, Denosumab (Xgeva), For Use In Patients With Solid Tumors – But Not Multiple Myeloma

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Hot "off the presses," here is yesterday afternoon's announcement from the FDA as reported by Reuters:FDA OKs Amgen's bone drug in certain cancersNov 18 2010 - By Deena Beasley* Denosumab approved for patients with solid tumors * Not approved for multiple myeloma* Shares rise 1.6 percent LOS ANGELES, Nov 18 (Reuters) - The U.S. Food

18 11, 2010

ImmunoGen, Inc To Present At American Society Of Hematology Meetings (ASH) In Orlando In Two Weeks

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Here is another pre-ASH press release from a drug company, ImmunoGen, I found posted on Marketwatch.com yesterday:Nov. 17, 2010ImmunoGen, Inc. Announces Clinical Data Presentations at the 52nd ASH Annual Meeting and Exposition WALTHAM, Mass., Nov 17, 2010 (BUSINESS WIRE) -- ImmunoGen, Inc., a biotechnology company that develops targeted antibody-based anticancer products, today announced that three presentations of

17 11, 2010

Update On Telomerase Inhibitor, Imetelstat (GRN163L)

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I just wrote a follow-up article about Geron's experimental telomerase inhibitor, imetelstat, on my other daily Website, HelpWithCancer.org:  More Positive Research News About Crossover Cancer Drug Imetelstat - Geron Announces Two Publications Demonstrating That Its Telomerase Inhibitor Drug Targets Cancer Stem Cells.I originally wrote about imetelstat back in April:  Geron, Maker Of Experimental Telomerase Inhibitor,

16 11, 2010

Reminder: Hernando County, Florida Multiple Myeloma Support Group Meets Tomorrow Night

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Our new HERNANDO COUNTY Multiple Myeloma Support Group meets tomorrow, November 17th, 2010 (3rd Wedesday of each month) at 6 PM.  GUEST SPEAKER: Jennifer Boldizsar, Oncology Specialistwith Millennium Pharmaceuticals.  A wonderful Italian meal from Carrabba's Italian Grill will be served.  There is no charge to attend.Spring Hill Enrichment Center - on the campus of Oak Hill

16 11, 2010

Is Mystery Drug, Cyclopamine, Potential Multiple Myeloma Cure?

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A regular reader contacted me several weeks ago, asking about a drug called cyclopamine.  I had never heard of the drug, but I promised to do some research about it.In his article titled Hedgehog Drugs Begin To Show Results, Ken Garber writes about what used to be called cyclopamine:When researchers announced last month that a hedgehog

15 11, 2010

England Makes Tough Decisions About Which Multiple Myeloma/Cancer Drugs To Allow

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Here is an in-depth, candid look at the English system of state controlled health care, where recommendations from a group of English physicians and medical experts known as NICE sometimes limits patient access to some drugs the group deems ineffective or too expensive.For example, NICE allows use of Thalomid or Velcade, but not Revlimid in

15 11, 2010

Bisphosphonate Day Today

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I'm writing this from the infusion unit at Moffitt Cancer Center here in Florida.  Time for my three month check and bisphosphonate infusion. My only concern:  Getting a good IV "stick" from my nurse.  It's only pain, right?  Let me get back to you in a few minutes and see how it goes... A super

14 11, 2010

Experimental Ovarian Cancer Drug, ENMD-2076, May Work Against Acute Myeloid Leukemia & Multiple Myeloma Too!

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Here is another pre-ASH press release from PRNewswire.com:ENMD-2076 Phase 1 Data in Hematological Studies to be Presented at ASHENMD-2076 Multiple Myeloma and Leukemia Abstracts to be Published in BloodROCKVILLE, Md., Nov. 9, 2010 /PRNewswire-FirstCall:EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer, today announced presentations for its Phase 2

13 11, 2010

New, Anti-Myeloma Viral Therapy, REOLYSIN, To Be Unveiled In Germany Later This Month

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Another new therapy with "anti-myeloma" properties was announced last week in Canada:CALGARY, Nov. 1 /PRNewswire - Oncolytics Biotech Inc. today announced that an abstract covering preclinical research with reovirus (REOLYSIN®) is available on the European CanCer Organisation (ECCO) website at www.ecco-org.eu. The research is scheduled to be presented at the 22nd EORTC-NCI-AACR symposium on Molecular

12 11, 2010

Reader Shares His Multiple Myeloma Story

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Late last month I received this e-mail comment from fellow patient Jack Searight, in response to my four part series of articles following my visit with multiple myeloma specialist Dr. James Berenson in Los Angeles.   Jack apparently had trouble getting Blogger to accept his comment.  From my experience, Jack's difficulties are not unusual.  I think