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Everything you ever wanted to know about proteasome inhibitors but were afraid to ask…

Home/Research, Therapy/Everything you ever wanted to know about proteasome inhibitors but were afraid to ask…

Everything you ever wanted to know about proteasome inhibitors but were afraid to ask…

Cancer Network is running a series I unofficially like to call “Everything you ever wanted to know about proteasome inhibitors but were afraid to ask.”

Maybe it should be “Too much information about proteasome inhibitors,” because some of this gets a bit heavy.

Here is a headline link to the first of two articles/studies on the subject:

Comparative Mechanisms of Action of Proteasome Inhibitors

By Michael Wang, MD | November 7, 2011
Department of Lymphoma & Myeloma, MD Anderson Cancer Center, Houston, Texas
Next, here is a comprehensive rundown about new proteasome inhibitor therapies currently in the research pipeline.  I thought this was very interesting:

Current Advances in Novel Proteasome Inhibitor–Based Approaches to the Treatment of Relapsed/Refractory Multiple Myeloma

By Sagar Lonial, MD,  Winship Cancer Institute and Lawrence H. Boise, PhD, Emory University Shool of Medicine, Atlanta, Georgia – November 7, 2011

As I continue to research and edit my new book one the subject, New Myeloma Therapies from a Patient’s Perspective, it is clear to me how important this type of therapy is going to be for decades to come. Now if researchers could only get around the stubborn, life-ending challenge of turning-off the switch in myeloma cells that allows them to adapt so quickly and become drug resistant…

Keep trying, research guys and gals!  Your work is much appreciated.
Feel good and keep smiling!  Pat