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BREAKING NEWS: HIV drug may help Velcade and Kyprolis work better

Home/News, Research/BREAKING NEWS: HIV drug may help Velcade and Kyprolis work better

BREAKING NEWS: HIV drug may help Velcade and Kyprolis work better

 

I haven’t had a chance to review the data yet, but Danny Parker forwarded me these links moments ago:

Pat,
This just off the medical press and called out by Dr. Robert Orlowski.

Oral protease inhibitor, Nelfinavir, used against HIV, enhances the activity of Bortezomib against myeloma. Even more important, it appears to overcome resistance in myeloma cells to Bortezomib or Carfilzomib.

http://www.ncbi.nlm.nih.gov/pubmed/23454896

Full text:
http://www.nature.com/bcj/journal/v3/n3/full/bcj20132a.html

Another article:
http://www.nature.com/cddis/journal/v3/n7/full/cddis201287a.html

Clinical trials under way:
http://clinicaltrials.gov/show/NCT01164709

http://clinicaltrials.gov/show/NCT01555281

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Thanks, Danny!  See what you think everybody and please chime-in.  Game changer or just another myeloma therapy “blip?”

Feel good and keep smiling!  Pat