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Hopeful news about research to overcome drug resistance to Velcade

Home/Research/Hopeful news about research to overcome drug resistance to Velcade

Hopeful news about research to overcome drug resistance to Velcade

A number of readers have excitedly forwarded me links to an article that has run on a number of different websites, Cancer researchers discover root cause of multiple myeloma relapse.

The PR piece is about researchers at Princess Margaret Cancer Centre and their work centering on a pair of genes (IRE1 and XBP1) that “modulate response to the proteasome inhibitor, Velcade, and the mechanism underlying the drug resistance that is the barrier to cure.”

A novel approach, but not a new one.  Doctors at Dana-Farber had focused on these genes for years, too.

Here’s a picture featuring Dr. Rodger Tiedemann, lead investigator on the team claiming to discover why multiple myeloma becomes resistant to treatment:

Dr

The nice thing about the article; it features an interesting video clip.  Here’s the link:

http://medicalxpress.com/news/2013-09-cancer-root-multiple-myeloma-relapse.html

This should remind us that a cure may be sitting right under researcher’s noses!  All they need to do is find a way to make the drugs we have now more effective and longer lasting.

Feel good and keep smiling!  Pat