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26 06, 2015

Play the odds: What happens if your therapy doesn’t work?

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I wanted to backtrack and focus on what may be the most important factor when analyzing the state of my multiple myeloma: my dwindling number of therapy options. Yesterday I wrote: Apparently my current therapy combination of Cytoxan, carfilzomib (Kyprolis) and dex (CCd) was not as effective as Dr. Tricot had hoped.  He told me

17 05, 2015

Therapy karma catches up to me

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I understand some of you have endured difficult side effects while using Revlimid and/or Velcade.  Sure, walking around borderline neutropenic often left me feeling a bit fatigued.  But I was one of the lucky ones; except for later in the day of RVD therapy--which left me feeling wiped-out and fluish--Rev and Velcade were no big

13 04, 2015

Cytoxan works surprisingly well for some patients

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Such a simple abstract, with so many lessons to learn.  Example of how Cytoxan and dex--at low doses--helped a relapsed patient in kidney failure stay stable for almost two years: Long-term Control in a Patient with Refractory Multiple Myeloma by Oral Cyclophosphamide and Dexamethasone Abstract Background: Prognosis of patients with multiple myeloma (MM) has substantially

7 12, 2013

Why doctors shouldn’t discard tried and true therapies for shiny new models

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Yesterday I wrote about the first half of the pre-ASH symposium, Critical Issues Need Answers: Providing Best Options for Myeloma Treatment in 2013. Picking up where I left off Friday, Dr. Jesus San-Miguel argued for using melphalan as part of induction therapy for elderly patients.  Interestingly, fellow European, Italian Dr. Antonio Palumbo, argued no.  Rarely

31 10, 2013

When it comes to myeloma, two heads are better than one!

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I met with my medical oncologist, Dr. Vikas Malhotra, for the first time since last month's relapse today.  He reviewed my test results, including the MRI of my left hip.  It reminded me why working together as a team is so important. I felt that Dr. Malhotra and his physicians assistant, Ann, made some innovative

27 03, 2012

Treat multiple myeloma like it’s a marathon–not a sprint!

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The Myeloma Beacon's Virginia Li wrote an interesting report late last week, highlighting how "more is not necessarily better" when it comes to myeloma therapy. Here is the first part of her article: Among Velcade-Based Combinations, Four-Drug Combo Is Not More Effective Than Similar Three-Drug Combos For Newly Diagnosed Multiple Myeloma The results of a

11 12, 2011

Full coverage of Friday evening IMF Satellite Symposium event (Part Three)

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I know, I know.  I'm falling behind!  I'm so busy collecting and analyzing newly released myeloma related research data, I have barely had time to write. Here is the final installment of my three part report about the IMF's Friday evening Satellite Symposium. I saved the best for last!  Dr. Robert Orlowski with M.D. Anderson