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Kyprolis

Home/Tag:Kyprolis
24 01, 2016

FDA expands access to Kyprolis. Big news?

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Friday the FDA expanded it's approval of how and when carfilzomib (Kyprolis) can be used. Trumpets sounded. I counted eleven industry news outlets that led with the story. My reaction? Big yawn. I wasn't even going to post about it. But Saturday a half dozen more publications ran stories about it, so I felt we

5 01, 2016

Stem cell transplant fallout front and center in 2016 (Part Two)

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I kicked off my 2016 posts yesterday this way: "Euphoria over a myeloma free PET scan doesn't make everything else OK. I've been struggling with post transplant side effects... Still plenty of drama to kick off 2016." Monday I wrote about how stressful insurance mix-ups can be. And I didn't even get into the financial

10 07, 2015

Another positive step toward myeloma awareness

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I was pleasantly surprised to find this high profile article on line yesterday Triple Drug Tx Effective for Smoldering Multiple Myeloma A new standard of care? MEDPAGETODAY - Sanjay Gupta, M.D., Editor Contributing Writer: Pam Harrison July 8th, 2015 Further evidence has emerged that supports the safety and efficacy of a proteasome inhibitor-immunomodulatory drug combination

26 06, 2015

Play the odds: What happens if your therapy doesn’t work?

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I wanted to backtrack and focus on what may be the most important factor when analyzing the state of my multiple myeloma: my dwindling number of therapy options. Yesterday I wrote: Apparently my current therapy combination of Cytoxan, carfilzomib (Kyprolis) and dex (CCd) was not as effective as Dr. Tricot had hoped.  He told me

1 06, 2015

Kyprolis may soon be infused once a week

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Kyprolis is a new, FDA approved proteasome inhibitor, similar to Velcade.  Early on, doctors learned that administering Velcade once weekly worked as well as the FDA approved twice weekly dosing.  Now Amgen, new owners of Onyx Pharmaceuticals and Kyprolis, have initiated a large clinical trial to try and prove the same for Kyprolis. Let's face

17 05, 2015

Therapy karma catches up to me

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I understand some of you have endured difficult side effects while using Revlimid and/or Velcade.  Sure, walking around borderline neutropenic often left me feeling a bit fatigued.  But I was one of the lucky ones; except for later in the day of RVD therapy--which left me feeling wiped-out and fluish--Rev and Velcade were no big

28 04, 2015

It’s the dex!

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Dr. Tricot chose to administer CcD every other week, so my bone marrow would have time to recover between cycles.  I started round two of my Cytoxan/Kyprolis/dexamethasone (CcD) yesterday afternoon.  If you recall, the combination really wiped me out two weeks ago. So I get Kyprolis infusions (common name, carfilzomib; hence the small "c") on

3 03, 2015

Kyprolis “superior” to Velcade?

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There has been a surprising amount of myeloma related news lately; the FDA's approval of panobinostat last week, and now the early release of data apparently showing that Kyprolis helps keep a relapsed patient's myeloma at bay longer than Velcade. My friends at Onyx (now part of Amgen) forwarded me the release announcing the news