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28 11, 2015

Blood Glucose, MGUS, Myeloma & Metformin (Part Five)

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Earlier this week, Danny Parker posted some compelling evidence that a drug commonly used to help control blood sugar in diabetics, metformin, may possess significant anti-myeloma properties. But could it work even better when combined with other drugs? Here's Danny's next installment: Metformin and Ritonavir as Potential Therapeutic Agents? As we described last time, there

30 12, 2014

Who knew? HIV and diabetes drugs cause myeloma cells to self destruct

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Sometimes medicines created to fix one thing end up working for something else, too.  I'm fascinated by the prospects that existing drugs--most likely used in unexpected combinations--may work against multiple myeloma, help us live longer.   Here's an example. Apparently the HIV drug, ritonavir, and diabetes drug, metformin, are toxic to myeloma cells.  Will the accidental